Make sure you don't ruin the fun before it starts. Get your boat to the marina safely by insuring your trailer tires are in towing shape.
Since the function your trailer performs is based largely on its tires, it's a good idea to keep your trailer tires well maintained. In many cases, especially with large trailers, the added weight the tires support even when stationary can cause trailer tires to wear out significantly faster than the tires on your coach vehicle.
If your trailer's been sitting around unused for a while, it's a good bet the tires could use inflating. Using your trailer often can obviously lead to loss of air pressure, but tires also lose pressure when not in use. All tires leak air over time, and so keeping an eye on your air pressure is essential to keeping your trailer properly maintained.